Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 6/20 | 0.35 |
| ▸ | TDO2 | P48775 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15621391 | 1.00 | KDM4E (0.59) | KDM4EPOLBMAPTIDO1TDO2 | |
| SCHEMBL19610699 | 0.87 | KDM4E (0.55) | KDM4EPOLBMAPTCYP1A2CYP3A4 | |
| SCHEMBL19610732 | 0.87 | KDM4E (0.55) | KDM4EPOLBMAPTIDO1TDO2 | |
| SCHEMBL30658812 | 0.87 | KDM4E (0.55) | KDM4EPOLBMAPTCYP1A2CYP3A4 | |
| SCHEMBL15619911 | 0.80 | KDM4E (0.67) | KDM4EPOLBMAPTIDO1CYP1A2 | |
| SCHEMBL29851825 | 0.80 | KDM4E (0.67) | KDM4EPOLBMAPTIDO1CYP1A2 | |
| SCHEMBL15620465 | 0.79 | KDM4E (0.60) | KDM4EPOLBMAPTCYP1A2CYP3A4 | |
| SCHEMBL30658740 | 0.79 | KDM4E (0.60) | KDM4EPOLBMAPTCYP1A2CYP3A4 | |
| SCHEMBL15620327 | 0.79 | POLB (0.70) | KDM4EPOLBMAPTCYP1A2CYP3A4 | |
| SCHEMBL15621079 | 0.78 | KDM4E (0.59) | KDM4EPOLBMAPTIDO1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818660-B | Beta-hydroxylase inhibitors for the treatment of cancer | 罗得岛医院 | 2023-09-12 | — | — | CN | disclosed |
| US-20220251076-A1 | Inhibitors of Beta-Hydoxylase for Treatment of Cancer | MIDWESTERN UNIVERSITY | 2022-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220251076-A1 | Inhibitors of Beta-Hydoxylase for Treatment of Cancer | ASPH, HAGH, FAH | KDM4E 696/4885POLB 1669/4885MAPT 3925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.