SCHEMBL30658985

SCHEMBL30658985

Clc1nc2c(ccc3ccccc32)nc1-c1ccc2ccccc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.41
PKM P14618 2/20 0.41
MAPK9 P45984 2/20 0.41
MAPK10 P53779 2/20 0.41
MAPK8 P45983 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
DHODH Q02127 1/20 0.40
PRMT5 O14744 1/20 0.39
PRMT3 O60678 1/20 0.39
CARM1 Q86X55 1/20 0.39
EHMT2 Q96KQ7 1/20 0.39
PRMT6 Q96LA8 1/20 0.39
PRMT1 Q99873 1/20 0.39
WDR77 Q9BQA1 1/20 0.39
HTR2B P41595 1/20 0.39
HTR5A P47898 1/20 0.39
MAPT P10636 4/20 0.39
SRC P12931 1/20 0.38
LMNA P02545 2/20 0.38
HTT P42858 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19784813 1.00 KDM4E (0.41) KDM4EPKMMAPK9MAPK10MAPK8
SCHEMBL28524984 0.94 KDM4E (0.41) KDM4EPKMMAPK9MAPK10MAPK8
SCHEMBL30762137 0.94 KDM4E (0.41) KDM4EPKMMAPK9MAPK10MAPK8
SCHEMBL21941950 0.86 KDM4E (0.54) KDM4EPKML3MBTL1DHODHPRMT5
SCHEMBL21282002 0.86 KDM4E (0.58) KDM4EPKML3MBTL1PRMT5PRMT3
SCHEMBL29994028 0.86 KDM4E (0.58) KDM4EPKML3MBTL1PRMT5PRMT3
SCHEMBL29995528 0.80 KDM4E (0.63) KDM4EPKMMAPK9MAPK10MAPK8
SCHEMBL19816496 0.80 KDM4E (0.63) KDM4EPKMMAPK9MAPK10MAPK8
SCHEMBL23438410 0.80 KDM4E (0.58) KDM4EPKML3MBTL1PRMT5PRMT3
SCHEMBL21941953 0.79 KDM4E (0.46) KDM4EPKML3MBTL1DHODHPRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112262135-B Heterocyclic compound and organic light-emitting device comprising same 株式会社LG化学 2023-10-24 CN disclosed