SCHEMBL21282002

SCHEMBL21282002

Clc1nc2c(ccc3ccccc32)nc1-c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.58
PKM P14618 1/20 0.58
L3MBTL1 Q9Y468 4/20 0.44
LMNA P02545 4/20 0.43
GAA P10253 2/20 0.43
MAPT P10636 3/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
RECQL P46063 1/20 0.42
PRMT5 O14744 1/20 0.42
PRMT3 O60678 1/20 0.42
CARM1 Q86X55 1/20 0.42
EHMT2 Q96KQ7 1/20 0.42
PRMT6 Q96LA8 1/20 0.42
PRMT1 Q99873 1/20 0.42
WDR77 Q9BQA1 1/20 0.42
ALDH1A1 P00352 4/20 0.41
GLA P06280 2/20 0.41
HPGD P15428 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29994028 1.00 KDM4E (0.58) KDM4EPKML3MBTL1LMNAGAA
SCHEMBL21941950 0.97 KDM4E (0.54) KDM4EPKML3MBTL1LMNAGAA
SCHEMBL23438410 0.93 KDM4E (0.58) KDM4EPKML3MBTL1LMNAGAA
SCHEMBL15818339 0.86 LMNA (0.47) KDM4EPKML3MBTL1LMNAGAA
SCHEMBL19784813 0.86 KDM4E (0.41) KDM4EPKML3MBTL1LMNAGAA
SCHEMBL30658985 0.86 KDM4E (0.41) KDM4EPKML3MBTL1LMNAGAA
SCHEMBL21707337 0.84 KDM4E (0.62) KDM4EPKML3MBTL1LMNAGAA
SCHEMBL21941953 0.83 KDM4E (0.46) KDM4EPKML3MBTL1LMNAMAPT
SCHEMBL14211981 0.83 KMT2A (0.46) KDM4EL3MBTL1LMNAGAAMAPT
SCHEMBL31326902 0.82 TDP1 (0.50) KDM4EL3MBTL1LMNAMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260020428-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2026-01-15 US disclosed
WO-2023160187-A1 CARBAZOLE DERIVATIVE AND USE THEREOF 上海八亿时空先进材料有限公司 2023-08-31 WO disclosed
WO-2023065996-A1 ANTHRACENE DERIVATIVE, ORGANIC ELECTROLUMINESCENT MATERIAL, LIGHT-EMITTING DEVICE, AND CONSUMER PRODUCT 上海八亿时空先进材料有限公司 2023-04-27 WO disclosed
WO-2022267839-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT, AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2022-12-29 WO disclosed
WO-2021230651-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-11-18 WO disclosed
WO-2021112478-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-06-10 WO disclosed
US-20210167297-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-06-03 US disclosed
WO-2019172623-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2019-09-12 WO disclosed
WO-2019160335-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2019-08-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210167297-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE AZI2, EZH2, EZH1 KDM4E 142/4885PKM 884/4885L3MBTL1 3573/4885
US-20260020428-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ORC3, KCNC1, EXOC1 KDM4E 2558/4885PKM 4446/4885L3MBTL1 617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.