Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.63 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.61 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.61 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.61 |
| ▸ | ECE1 | P42892 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | GHSR | Q92847 | 1/20 | 0.58 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.58 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.58 |
| ▸ | ITGAL | P20701 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1939431 | 1.00 | ACE (0.63) | ACEERAP2ERAP1LNPEPECE1 | |
| SCHEMBL1939435 | 1.00 | ACE (0.63) | ACEERAP2ERAP1LNPEPECE1 | |
| SCHEMBL29924977 | 0.97 | GHSR (0.60) | ACEERAP2ERAP1LNPEPECE1 | |
| SCHEMBL29925186 | 0.97 | GHSR (0.60) | ACEERAP2ERAP1LNPEPECE1 | |
| SCHEMBL31468798 | 0.97 | GHSR (0.60) | ACEERAP2ERAP1LNPEPECE1 | |
| SCHEMBL31253359 | 0.97 | ACE (0.64) | ACEERAP2ERAP1LNPEPECE1 | |
| SCHEMBL30659508 | 0.97 | ACE (0.64) | ACEERAP2ERAP1LNPEPECE1 | |
| SCHEMBL29578372 | 0.95 | GHSR (0.62) | ACEERAP2ERAP1LNPEPGHSR | |
| SCHEMBL3384748 | 0.95 | GHSR (0.62) | ACEERAP2ERAP1LNPEPGHSR | |
| SCHEMBL27702662 | 0.95 | GHSR (0.62) | ACEERAP2ERAP1LNPEPGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3716948-B1 | NOVEL ANALGESIC PHARMACEUTICAL FORMULATIONS AND USES THEREOF | CYTOGEL PHARMA LLC (US) | 2023-11-22 | — | — | EP | disclosed |