Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 7/20 | 0.62 |
| ▸ | ROS1 | P08922 | 6/20 | 0.62 |
| ▸ | EGFR | P00533 | 13/20 | 0.59 |
| ▸ | INSR | P06213 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26906900 | 0.91 | EGFR (0.59) | ALKROS1EGFR | |
| SCHEMBL26906870 | 0.90 | EGFR (0.60) | ALKROS1EGFRINSRIGF1R | |
| SCHEMBL29904636 | 0.87 | EGFR (0.58) | ALKROS1EGFR | |
| SCHEMBL29114865 | 0.87 | EGFR (0.63) | ALKROS1EGFRINSRIGF1R | |
| SCHEMBL26906651 | 0.87 | EGFR (0.66) | ALKROS1EGFRINSRIGF1R | |
| SCHEMBL29904679 | 0.87 | EGFR (0.66) | ALKROS1EGFRINSRIGF1R | |
| SCHEMBL29904689 | 0.87 | EGFR (0.63) | ALKROS1EGFRINSRIGF1R | |
| SCHEMBL25788902 | 0.79 | EGFR (0.52) | EGFR | |
| SCHEMBL22595122 | 0.78 | EGFR (0.75) | EGFR | |
| SCHEMBL30659720 | 0.77 | ALK (0.53) | ALKROS1EGFRINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120424-A | Pyrimidine derivatives having protein kinase inhibitory activity and therapeutic combinations comprising the same | 泰拉佩克斯有限公司 | 2023-11-24 | — | — | CN | claimed |
| CN-117120424-A | Pyrimidine derivatives having protein kinase inhibitory activity and therapeutic combinations comprising the same | 泰拉佩克斯有限公司 | 2023-11-24 | — | — | CN | disclosed |