Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22278392 | 1.00 | CCNB2 (0.46) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL28585711 | 0.84 | CDK1 (0.38) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL31539452 | 0.83 | MAPK1 (0.49) | MAPK1GAALMNAKMT2AMEN1 | |
| SCHEMBL7997935 | 0.82 | SMN1; SMN2 (0.61) | MAPK1GAALMNANPC1RAB9A | |
| SCHEMBL30660973 | 0.79 | MAPK1 (0.46) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL22278558 | 0.79 | MAPK1 (0.46) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL30660980 | 0.79 | MAPK1 (0.46) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL1253195 | 0.78 | CCNB2 (0.38) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL22278711 | 0.78 | MAPK1 (0.54) | MAPK1GAALMNARAB9AKMT2A | |
| SCHEMBL23152289 | 0.78 | ALDH1A1 (0.46) | MAPK1GAALMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112839931-B | 1,2,3, 4-tetrahydroquinoxaline derivative, and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-12-01 | — | — | CN | disclosed |