Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.46 |
| ▸ | BID | P55957 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.43 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21959654 | 0.85 | TRIM24 (0.41) | ALDH1A1TSHRMGLLTDP1L3MBTL1 | |
| SCHEMBL16058205 | 0.79 | BID (0.50) | NR1H2NR1H3LIPGBIDMCL1 | |
| SCHEMBL16058319 | 0.79 | BID (0.50) | NR1H2NR1H3LIPGBIDMCL1 | |
| SCHEMBL14975143 | 0.79 | BID (0.50) | NR1H2NR1H3LIPGBIDMCL1 | |
| SCHEMBL14977312 | 0.79 | BID (0.50) | NR1H2NR1H3LIPGBIDMCL1 | |
| SCHEMBL16057930 | 0.79 | BID (0.50) | NR1H2NR1H3LIPGBIDMCL1 | |
| SCHEMBL24618267 | 0.77 | TAAR1 (0.44) | ALDH1A1TSHR | |
| SCHEMBL31618496 | 0.77 | TRIM24 (0.39) | ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL20937700 | 0.74 | CYP2D6 (0.48) | LIPGGPR84ALDH1A1TP53HSP90AA1 | |
| SCHEMBL28080853 | 0.74 | CYP2D6 (0.48) | LIPGGPR84ALDH1A1TP53HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157285-A | Pharmaceutical compounds as ubiquitin-specific protease 19 (USP 19) inhibitors | 阿尔麦克探索有限公司 | 2023-12-01 | — | — | CN | disclosed |