Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GALR3 | O60755 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28080853 | 1.00 | CYP2D6 (0.48) | CYP2D6TBXAS1CNR2KCNH2GPR84 | |
| SCHEMBL11898919 | 1.00 | CYP2D6 (0.48) | CYP2D6TBXAS1CNR2KCNH2GPR84 | |
| Hydrochloric Acid SCHEMBL11899838 | 0.98 | CYP2D6 (0.47) | CYP2D6TBXAS1CNR2KCNH2GPR84 | |
| SCHEMBL7544246 | 0.98 | CYP2D6 (0.45) | CYP2D6TBXAS1CNR2KCNH2GPR84 | |
| SCHEMBL11900019 | 0.92 | CYP2D6 (0.42) | CYP2D6TBXAS1CNR2CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL11898482 | 0.90 | CYP2D6 (0.45) | CYP2D6TBXAS1CNR2CYP3A4CYP2C19 | |
| Bromide SCHEMBL28799569 | 0.90 | CYP2D6 (0.41) | CYP2D6TBXAS1CNR2CYP3A4CYP2C19 | |
| Fluoride SCHEMBL30330792 | 0.90 | CYP2D6 (0.41) | CYP2D6TBXAS1CNR2CYP3A4CYP2C19 | |
| SCHEMBL27966926 | 0.85 | TAAR1 (0.39) | CYP2D6TBXAS1CNR2CYP3A4CYP2C19 | |
| SCHEMBL7072643 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106265697-A | Salicylic acid mixture and preparation method thereof, salicylic acid ionic liquid solution and the purposes of ionic liquid | 武汉软件工程职业学院 | 2017-01-04 | — | — | CN | claimed |
| US-10888563-B2 | Fused heterotricyclic organic compounds, pharmaceutical compositions, and medical uses thereof | ALEVERE MEDICAL CORPORATION (US) | 2021-01-12 | — | — | US | disclosed |
| US-20190117656-A1 | FUSED HETEROTRICYCLIC ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ALEVERE MEDICAL CORPORATION | 2019-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190117656-A1 | FUSED HETEROTRICYCLIC ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | FABP4, HSD17B4, LIPC | CYP2D6 30/4885TBXAS1 189/4885CNR2 373/4885 |
| US-10888563-B2 | Fused heterotricyclic organic compounds, pharmaceutical compositions, and medical uses thereof | FABP4, HSD17B4, LIPC | CYP2D6 30/4885TBXAS1 189/4885CNR2 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.