Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 15/20 | 0.54 |
| ▸ | PARP11 | Q9NR21 | 14/20 | 0.54 |
| ▸ | PARP1 | P09874 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.37 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29144293 | 0.74 | PARP10 (0.56) | PARP10PARP11PARP1ALDH1A1LMNA | |
| SCHEMBL30019767 | 0.74 | PARP10 (0.56) | PARP10PARP11PARP1ALDH1A1LMNA | |
| SCHEMBL18577021 | 0.73 | PARP10 (0.60) | PARP10PARP11PARP1ALDH1A1KDM4E | |
| SCHEMBL831538 | 0.70 | PARP1 (1.00) | PARP10PARP11PARP1ACHEPDPK1 | |
| SCHEMBL29687894 | 0.70 | PARP1 (1.00) | PARP10PARP11PARP1ACHEPDPK1 | |
| SCHEMBL30019687 | 0.70 | PARP10 (0.50) | PARP10PARP11PARP1ALDH1A1LMNA | |
| SCHEMBL29144339 | 0.70 | PARP10 (0.50) | PARP10PARP11PARP1ALDH1A1LMNA | |
| SCHEMBL30833271 | 0.69 | PARP10 (0.56) | PARP10PARP11PARP1PDPK1 | |
| SCHEMBL18554689 | 0.69 | PARP10 (0.56) | PARP10PARP11PARP1PDPK1 | |
| SCHEMBL23952300 | 0.65 | PARP10 (0.56) | PARP10PARP11PARP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242073-A | PRMT5 inhibitors and uses thereof | 海思科医药集团股份有限公司 | 2023-12-15 | — | — | CN | disclosed |