Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.57 |
| ▸ | NAMPT | P43490 | 8/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30065703 | 0.88 | RORC (0.64) | RORCNAMPTALDH1A1CA2 | |
| SCHEMBL30065034 | 0.84 | TSHR (0.66) | RORCNAMPTTHRBALDH1A1TSHR | |
| SCHEMBL28705898 | 0.81 | RORC (0.60) | RORCNAMPTCA2 | |
| SCHEMBL23632693 | 0.81 | RORC (0.55) | RORCNAMPT | |
| SCHEMBL28715187 | 0.79 | RORC (0.57) | RORCNAMPTCA2 | |
| SCHEMBL19925258 | 0.78 | RORC (0.52) | RORCNAMPT | |
| SCHEMBL998521 | 0.77 | NPC1 (0.63) | THRBALDH1A1TSHRCA2SMN1; SMN2 | |
| SCHEMBL29415439 | 0.77 | NPC1 (0.63) | THRBALDH1A1TSHRCA2SMN1; SMN2 | |
| SCHEMBL28778419 | 0.76 | NAMPT (0.55) | RORCNAMPTALDH1A1CA2GAA | |
| SCHEMBL29754338 | 0.76 | NAMPT (0.55) | RORCNAMPTALDH1A1CA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800904-A | ROR gamma inhibitors containing sulfonyl structures | 正大天晴药业集团股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-113166061-B | ROR gamma inhibitors containing sulfonyl structures | 正大天晴药业集团股份有限公司 | 2023-11-21 | — | — | CN | disclosed |