Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299539 | 0.85 | BCL2L1 (0.46) | BCL2L1BADALDH1A1LMNAMEN1 | |
| SCHEMBL12930757 | 0.83 | ALDH1A1 (0.44) | BCL2L1BADALDH1A1LMNAMEN1 | |
| SCHEMBL24469462 | 0.78 | BCL2L1 (0.47) | BCL2L1BADALDH1A1LMNAMEN1 | |
| SCHEMBL20510102 | 0.78 | BCL2L1 (0.47) | BCL2L1BADALDH1A1LMNAMEN1 | |
| SCHEMBL17154225 | 0.78 | BCL2L1 (0.52) | BCL2L1BADALDH1A1LMNAMEN1 | |
| SCHEMBL19682589 | 0.77 | BCL2L1 (0.41) | BCL2L1BADALDH1A1LMNAMEN1 | |
| SCHEMBL20889215 | 0.77 | BCL2L1 (0.41) | BCL2L1BADALDH1A1LMNAMEN1 | |
| SCHEMBL19682588 | 0.77 | BCL2L1 (0.41) | BCL2L1BADALDH1A1LMNAMEN1 | |
| SCHEMBL18540425 | 0.77 | BCL2L1 (0.50) | BCL2L1BADALDH1A1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL29043115 | 0.76 | BCL2L1 (0.46) | BCL2L1BADALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267697-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267697-A1 | ION CHANNEL MODULATORS | CACNA1E, CACNA1A, CACNA1S | BCL2L1 1742/4885BAD 954/4885ALDH1A1 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.