Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19308338 | 1.00 | FAAH (0.40) | FAAHGPR84TDP1L3MBTL1KCNH2 | |
| SCHEMBL22647103 | 0.98 | FAAH (0.38) | FAAHGPR84TDP1L3MBTL1KCNH2 | |
| SCHEMBL23750446 | 0.93 | FAAH (0.35) | FAAHTDP1L3MBTL1KCNH2 | |
| SCHEMBL13848610 | 0.86 | FAAH (0.34) | FAAHKCNH2 | |
| SCHEMBL20442236 | 0.85 | FAAH (0.40) | FAAHTDP1L3MBTL1KCNH2LMNA | |
| SCHEMBL21661962 | 0.85 | FAAH (0.40) | FAAHTDP1L3MBTL1KCNH2LMNA | |
| SCHEMBL22308327 | 0.83 | FAAH (0.40) | FAAHTDP1L3MBTL1KCNH2LMNA | |
| SCHEMBL26078437 | 0.82 | FAAH (0.39) | FAAHTDP1L3MBTL1KCNH2LMNA | |
| SCHEMBL21360381 | 0.82 | NR1I2 (0.40) | FAAHTDP1L3MBTL1KCNH2LMNA | |
| SCHEMBL22460414 | 0.78 | TSHR (0.36) | TDP1L3MBTL1KCNH2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116924976-A | Diaryl heterocyclic amine compound, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2023-10-24 | — | — | CN | disclosed |