Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 7/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1982433 | 1.00 | PNMT (0.56) | PNMTADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL26656333 | 1.00 | PNMT (0.56) | PNMTADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL30697867 | 0.86 | PNMT (0.62) | PNMTADRA2AADRA2BADRA2CHTR2A | |
| SCHEMBL17018035 | 0.81 | PNMT (0.45) | PNMTADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL21172482 | 0.81 | PNMT (0.45) | PNMTADRA2AADRA2BADRA2CBRD4 | |
| SCHEMBL31511298 | 0.81 | PNMT (0.45) | PNMTADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL30294039 | 0.81 | PNMT (0.45) | PNMTADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL16585592 | 0.81 | PNMT (0.45) | PNMTADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL12965849 | 0.79 | AR (0.45) | PNMTADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL31188791 | 0.78 | PNMT (0.41) | PNMTADRA2AADRA2BADRA2CBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4526289-A1 | ANTIVIRAL INDOLINYL COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2025-03-26 | — | — | EP | disclosed |
| CN-119546574-A | Antiviral indolinyl compounds and uses thereof | 吉利德科学公司 | 2025-02-28 | — | — | CN | disclosed |
| WO-2023225162-A1 | ANTIVIRAL INDOLINYL COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-11-23 | — | — | WO | disclosed |