Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26656460 | 1.00 | FGFR2 (0.33) | FGFR2BRAFPDGFRAKDRALDH1A1 | |
| SCHEMBL26868109 | 1.00 | FGFR2 (0.33) | FGFR2BRAFPDGFRAKDRALDH1A1 | |
| SCHEMBL26868110 | 1.00 | FGFR2 (0.33) | FGFR2BRAFPDGFRAKDRALDH1A1 | |
| SCHEMBL26656446 | 0.87 | PTGS1 (0.37) | BRAFPDGFRAALDH1A1GRM1GAA | |
| SCHEMBL26866143 | 0.87 | PTGS1 (0.37) | BRAFPDGFRAALDH1A1GRM1GAA | |
| SCHEMBL26866144 | 0.87 | PTGS1 (0.37) | BRAFPDGFRAALDH1A1GRM1GAA | |
| SCHEMBL25464961 | 0.85 | KDR (0.41) | FGFR2PDGFRAKDR | |
| SCHEMBL25467132 | 0.85 | KDR (0.41) | FGFR2PDGFRAKDR | |
| SCHEMBL30666116 | 0.82 | BRAF (0.36) | FGFR2BRAFPDGFRAKDRALDH1A1 | |
| SCHEMBL26863362 | 0.82 | BRAF (0.36) | FGFR2BRAFPDGFRAKDRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225001-A1 | NAPHTHYRIDINE BASED ENPP1 MODULATORS AND USES THEREOF | Vir Biotechnology, Inc. (US) | 2023-11-23 | — | — | WO | disclosed |