Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26683430 | 1.00 | OXTR (0.42) | OXTRAVPR1AEHMT2KRASACACB | |
| SCHEMBL26683610 | 0.88 | OXTR (0.43) | OXTRAVPR1AEHMT2KRASACACB | |
| SCHEMBL26683384 | 0.85 | OXTR (0.39) | OXTRAVPR1AEHMT2MEN1KMT2A | |
| SCHEMBL30666275 | 0.85 | OXTR (0.39) | OXTRAVPR1AEHMT2MEN1KMT2A | |
| SCHEMBL26683319 | 0.83 | SMARCA2 (0.45) | OXTRAVPR1AEHMT2KRASSCD5 | |
| SCHEMBL30666273 | 0.79 | OXTR (0.45) | OXTRAVPR1AEHMT2KRASACACB | |
| SCHEMBL26683651 | 0.79 | OXTR (0.45) | OXTRAVPR1AEHMT2KRASACACB | |
| SCHEMBL30666276 | 0.75 | MAPT (0.44) | MEN1KMT2ANPSR1TP53POLB | |
| SCHEMBL26683361 | 0.75 | MAPT (0.44) | MEN1KMT2ANPSR1TP53POLB | |
| SCHEMBL26683423 | 0.75 | MAPT (0.43) | MEN1KMT2ANPSR1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522277-A1 | PYRAZINE DERIVATIVES AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220137-A1 | PYRAZINE DERIVATIVES AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |