Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 10/20 | 0.46 |
| ▸ | PPOX | P50336 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25692990 | 1.00 | STING1 (0.46) | STING1PPOXACHEMTNR1AMTNR1B | |
| SCHEMBL30416824 | 0.87 | STING1 (0.59) | STING1ACHE | |
| SCHEMBL21405764 | 0.87 | STING1 (0.59) | STING1ACHE | |
| SCHEMBL21405800 | 0.81 | STING1 (0.44) | STING1ACHEMTNR1AMTNR1BLIPG | |
| SCHEMBL30416428 | 0.81 | STING1 (0.44) | STING1ACHEMTNR1AMTNR1BLIPG | |
| SCHEMBL21454848 | 0.80 | STING1 (0.52) | STING1ACHE | |
| SCHEMBL21437180 | 0.79 | STING1 (0.54) | STING1 | |
| SCHEMBL25855979 | 0.79 | STING1 (0.48) | STING1 | |
| SCHEMBL21405952 | 0.78 | STING1 (0.49) | STING1PTPN2 | |
| SCHEMBL21406350 | 0.77 | STING1 (0.53) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117203194-A | Novel compounds useful as STING agonists and uses thereof | 北京加科思新药研发有限公司 | 2023-12-08 | — | — | CN | disclosed |