Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29119987 | 1.00 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2GAACYP2C19 | |
| SCHEMBL30416446 | 0.83 | CYP2C19 (0.49) | MEN1KMT2ASMN1; SMN2GAACYP2C19 | |
| SCHEMBL3935344 | 0.80 | ALDH1A1 (0.45) | MEN1KMT2ASMN1; SMN2GAACYP2C19 | |
| SCHEMBL1127424 | 0.80 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2GAACYP2C19 | |
| SCHEMBL11532666 | 0.80 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2GAACYP2C19 | |
| SCHEMBL13619600 | 0.80 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2GAACYP2C19 | |
| SCHEMBL29099538 | 0.79 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2GAACYP2C19 | |
| SCHEMBL1127868 | 0.79 | MEN1 (0.59) | MEN1KMT2ASMN1; SMN2GAACYP2C19 | |
| SCHEMBL1162993 | 0.79 | SMN1; SMN2 (0.66) | MEN1KMT2ASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL27103723 | 0.78 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2GAACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117203194-A | Novel compounds useful as STING agonists and uses thereof | 北京加科思新药研发有限公司 | 2023-12-08 | — | — | CN | disclosed |