Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL191702 | 0.89 | AKT1 (0.36) | LIMK1AKT1AKT2AKT3 | |
| SCHEMBL12294286 | 0.79 | LIMK1 (0.54) | LIMK1POLBHTTL3MBTL1HRH2 | |
| SCHEMBL857565 | 0.75 | — | — | |
| SCHEMBL30666480 | 0.74 | LIMK1 (0.33) | LIMK1POLBHTTL3MBTL1HRH2 | |
| SCHEMBL30666659 | 0.74 | LIMK1 (0.33) | LIMK1POLBHTTL3MBTL1HRH2 | |
| SCHEMBL30667010 | 0.74 | LIMK1 (0.33) | LIMK1POLBHTTL3MBTL1HRH2 | |
| SCHEMBL30667148 | 0.71 | LIMK1 (0.32) | LIMK1 | |
| SCHEMBL3665082 | 0.70 | AKT1 (0.31) | AKT1AKT2AKT3 | |
| SCHEMBL3669632 | 0.70 | AKT1 (0.32) | AKT1AKT2AKT3 | |
| SCHEMBL17771795 | 0.68 | LIMK1 (0.33) | LIMK1AKT1AKT2AKT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116940552-A | Spirocyclic hexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2023-10-24 | — | — | CN | disclosed |