SCHEMBL306680

SCHEMBL306680

CCOC(=O)C1=NN(c2ccccc2)C(=O)C1/N=N/c1ccc(-c2ccc(/N=N/C3C(=O)N(c4ccccc4)N=C3C(=O)OCC)c(Cl)c2)cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.43
▸ SMN1; SMN2 Q16637 4/20 0.43
▸ ALDH1A1 P00352 4/20 0.43
▸ NPC1 O15118 3/20 0.43
▸ LMNA P02545 2/20 0.43
▸ TDP1 Q9NUW8 2/20 0.43
▸ RAB9A P51151 2/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ MEN1 O00255 5/20 0.42
▸ KMT2A Q03164 5/20 0.42
▸ GAA P10253 4/20 0.41
▸ ATM Q13315 1/20 0.40
▸ KDM4E B2RXH2 2/20 0.39
▸ POLB P06746 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ CYP1A2 P05177 2/20 0.38
▸ CYP2D6 P10635 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ GABRA2 P47869 3/20 0.38
▸ GABRB2 P47870 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29357349 1.00 MAPT (0.43) MAPTSMN1; SMN2ALDH1A1NPC1LMNA
SCHEMBL306681 1.00 MAPT (0.43) MAPTSMN1; SMN2ALDH1A1NPC1LMNA
SCHEMBL21436310 0.88 GAA (0.44) MAPTSMN1; SMN2ALDH1A1NPC1LMNA
SCHEMBL29351685 0.88 GAA (0.44) MAPTSMN1; SMN2ALDH1A1NPC1LMNA
SCHEMBL30388957 0.84 MAPT (0.56) MAPTSMN1; SMN2ALDH1A1NPC1LMNA
SCHEMBL30078720 0.82 MAPT (0.64) MAPTSMN1; SMN2ALDH1A1NPC1LMNA
SCHEMBL2641828 0.82 MAPT (0.64) MAPTSMN1; SMN2ALDH1A1NPC1LMNA
SCHEMBL2641824 0.82 MAPT (0.64) MAPTSMN1; SMN2ALDH1A1NPC1LMNA
SCHEMBL29350167 0.82 MAPT (0.64) MAPTSMN1; SMN2ALDH1A1NPC1LMNA
SCHEMBL2612569 0.80 KMT2A (0.45) MAPTSMN1; SMN2ALDH1A1NPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8092963-B2 Toner compositions XEROX CORPORATION (US) 2012-01-10 — — US claimed
EP-3679087-B1 SILICONE-FREE THERMAL GEL HONEYWELL INT INC (US) 2024-02-14 — — EP disclosed
EP-3839005-B1 THERMAL INTERFACE MATERIALS INCLUDING COLORING AGENT HONEYWELL INT INC (US) 2023-07-19 — — EP disclosed
EP-3839005-A1 THERMAL INTERFACE MATERIALS INCLUDING COLORING AGENT Honeywell International Inc. (US) 2021-06-23 — — EP disclosed
US-11041103-B2 Silicone-free thermal gel HONEYWELL INTERNATIONAL INC. (US) 2021-06-22 — — US disclosed
US-11041103-B2 Silicone-free thermal gel HONEYWELL INTERNATIONAL INC. (US) 2021-06-22 — — US disclosed
US-10428256-B2 Releasable thermal gel HONEYWELL INTERNATIONAL INC. (US) 2019-10-01 — — US disclosed
US-10428256-B2 Releasable thermal gel HONEYWELL INTERNATIONAL INC. (US) 2019-10-01 — — US disclosed
US-10312177-B2 Thermal interface materials including a coloring agent HONEYWELL INTERNATIONAL INC. (US) 2019-06-04 — — US disclosed
US-10312177-B2 Thermal interface materials including a coloring agent HONEYWELL INTERNATIONAL INC. (US) 2019-06-04 — — US disclosed
US-20190119544-A1 RELEASABLE THERMAL GEL SOLSTICE ADVANCED MATERIALS US, INC. 2019-04-25 — — US disclosed
US-20190119544-A1 RELEASABLE THERMAL GEL SOLSTICE ADVANCED MATERIALS US, INC. 2019-04-25 — — US disclosed
US-20190078007-A1 SILICONE-FREE THERMAL GEL SOLSTICE ADVANCED MATERIALS US, INC. 2019-03-14 — — US disclosed
US-20190078007-A1 SILICONE-FREE THERMAL GEL SOLSTICE ADVANCED MATERIALS US, INC. 2019-03-14 — — US disclosed
US-20180358283-A1 THERMAL INTERFACE MATERIALS INCLUDING A COLORING AGENT SOLSTICE ADVANCED MATERIALS US, INC. 2018-12-13 — — US disclosed
US-9362514-B2 Polarization organic photoelectric conversion device, method for producing polarization organic photoelectric conversion device, polarization optical device, imaging device, and electronic apparatus SONY CORPORATION (JP) 2016-06-07 — — US disclosed
US-9362514-B2 Polarization organic photoelectric conversion device, method for producing polarization organic photoelectric conversion device, polarization optical device, imaging device, and electronic apparatus SONY CORPORATION (JP) 2016-06-07 — — US disclosed
US-20120248563-A1 POLARIZATION ORGANIC PHOTOELECTRIC CONVERSION DEVICE, METHOD FOR PRODUCING POLARIZATION ORGANIC PHOTOELECTRIC CONVERSION DEVICE, POLARIZATION OPTICAL DEVICE, IMAGING DEVICE, AND ELECTRONIC APPARATUS SONY CORPORATION (JP) 2012-10-04 — — US disclosed
US-20120248563-A1 POLARIZATION ORGANIC PHOTOELECTRIC CONVERSION DEVICE, METHOD FOR PRODUCING POLARIZATION ORGANIC PHOTOELECTRIC CONVERSION DEVICE, POLARIZATION OPTICAL DEVICE, IMAGING DEVICE, AND ELECTRONIC APPARATUS SONY CORPORATION (JP) 2012-10-04 — — US disclosed
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