SCHEMBL21436310

SCHEMBL21436310

CCOC(=O)C1=NN(c2ccccc2)C(=O)C1N=Nc1ccc(-c2ccc(N=NC3C(=O)N(c4ccccc4)N=C3C(=O)OCC)c(OC)c2)cc1OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 2/20 0.44
▸ KDM4E B2RXH2 2/20 0.44
▸ KMT2A Q03164 5/20 0.44
▸ MEN1 O00255 3/20 0.44
▸ ATM Q13315 1/20 0.44
▸ PDE4A P27815 10/20 0.42
▸ PDE4B Q07343 10/20 0.42
▸ PDE4C Q08493 10/20 0.42
▸ PDE4D Q08499 10/20 0.42
▸ MAPT P10636 4/20 0.42
▸ TDP1 Q9NUW8 3/20 0.42
▸ NPC1 O15118 2/20 0.42
▸ ALDH1A1 P00352 2/20 0.42
▸ LMNA P02545 2/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ RAB9A P51151 1/20 0.42
▸ POLB P06746 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351685 1.00 GAA (0.44) GAAKDM4EKMT2AMEN1ATM
SCHEMBL2612569 0.92 KMT2A (0.45) GAAKDM4EKMT2AMEN1ATM
SCHEMBL306681 0.88 MAPT (0.43) GAAKDM4EKMT2AMEN1ATM
SCHEMBL306680 0.88 MAPT (0.43) GAAKDM4EKMT2AMEN1ATM
SCHEMBL29357349 0.88 MAPT (0.43) GAAKDM4EKMT2AMEN1ATM
SCHEMBL30388957 0.83 MAPT (0.56) GAAKDM4EKMT2AMEN1ATM
SCHEMBL9451197 0.83 KMT2A (0.62) GAAKDM4EKMT2AMEN1ATM
SCHEMBL29355605 0.83 KMT2A (0.62) GAAKDM4EKMT2AMEN1ATM
SCHEMBL9231057 0.82 PDE4A (0.49) KDM4EKMT2AMEN1ATMPDE4A
SCHEMBL21611730 0.76 KMT2A (0.52) GAAKDM4EKMT2AMEN1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230310300-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER HFC PRESTIGE SERVICE GERMINY GMBH (DE) 2023-10-05 — — US disclosed
EP-4171500-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER Wella Germany GmbH (DE) 2023-05-03 — — EP disclosed
US-11324688-B2 Bicomponent composition WELLA INTERNATIONAL OPERATIONS SWI (CH) 2022-05-10 — — US disclosed
US-20220054392-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION WELLA INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2022-02-24 — — US disclosed
US-20220016017-A1 COLOR COATINGS WITH DOWNSTREAM FEATURES HFC PRESTIGE SERVICE GERMANY GMBH (DE) 2022-01-20 — — US disclosed
WO-2022002983-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER HFC PRESTIGE SERVICE GERMANY GMBH (DE) 2022-01-06 — — WO disclosed
EP-3890683-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-10-13 — — EP disclosed
US-20210290519-A1 MULTICOMPONENT SILICONE COMPOSITION WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2021-09-23 — — US disclosed
US-20210290518-A1 MULTICOMPONENT COMPOSITION HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2021-09-23 — — US disclosed
US-20210145726-A1 BICOMPONENT COMPOSITION HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2021-05-20 — — US disclosed
EP-3817710-A1 MULTICOMPONENT SILICONE COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-05-12 — — EP disclosed
EP-3817825-A1 MULTICOMPONENT PUR COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-05-12 — — EP disclosed
EP-3787753-A1 MULTICOMPONENT COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-03-10 — — EP disclosed
EP-3773922-A1 BICOMPONENT COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-02-17 — — EP disclosed
WO-2020114647-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-06-11 — — WO disclosed
WO-2020007510-A1 MULTICOMPONENT PUR COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-01-09 — — WO disclosed
WO-2020007511-A1 MULTICOMPONENT SILICONE COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-01-09 — — WO disclosed
WO-2019192916-A1 BICOMPONENT COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2019-10-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220016017-A1 COLOR COATINGS WITH DOWNSTREAM FEATURES KRT18, ITGA5, FLNA GAA 4258/4885KDM4E 78/4885KMT2A 586/4885
US-20230310300-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER KRT18, MKI67, IK GAA 4594/4885KDM4E 746/4885KMT2A 876/4885
US-20210290519-A1 MULTICOMPONENT SILICONE COMPOSITION CUTA, CD99, PLOD3 GAA 4572/4885KDM4E 911/4885KMT2A 648/4885
US-20220054392-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION KRT18, PRKDC, VIM GAA 4800/4885KDM4E 1286/4885KMT2A 1653/4885
US-11324688-B2 Bicomponent composition KRT18, EXOSC10, EXOSC9 GAA 4590/4885KDM4E 1673/4885KMT2A 1253/4885
US-20210290518-A1 MULTICOMPONENT COMPOSITION KRT18, INCENP, IK GAA 4725/4885KDM4E 84/4885KMT2A 684/4885
US-20210145726-A1 BICOMPONENT COMPOSITION KRT18, EXOSC10, EXOSC9 GAA 4590/4885KDM4E 1673/4885KMT2A 1253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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