Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 4/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | STS | P08842 | 2/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22954042 | 1.00 | KAT6A (0.57) | KAT6AATMTDP1L3MBTL1STS | |
| SCHEMBL690501 | 0.95 | KAT6A (0.54) | KAT6AATMTDP1L3MBTL1STS | |
| SCHEMBL9229632 | 0.86 | POLB (0.55) | KAT6AATMGPR139ALDH1A1MRGPRX4 | |
| SCHEMBL29459930 | 0.86 | MRGPRX4 (0.61) | KAT6AGPR139TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL496275 | 0.86 | MRGPRX4 (0.61) | KAT6AGPR139TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL14297682 | 0.85 | ELANE (0.49) | KAT6AATMSTSGPR139TAS1R3 | |
| SCHEMBL4602009 | 0.84 | ELANE (0.56) | STSSRD5A2ALDH1A1MRGPRX4 | |
| SCHEMBL22954272 | 0.83 | IGF2BP2 (0.46) | KAT6AATMTDP1L3MBTL1STS | |
| SCHEMBL28208860 | 0.82 | KAT6A (0.52) | KAT6AGPR139MAPK14TAS1R3TAS1R1 | |
| SCHEMBL10561497 | 0.82 | KAT6A (0.52) | KAT6AGPR139MAPK14TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YROK (US) | 2023-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | AFF2, AFF4, AFF1 | KAT6A 1660/4885ATM 2456/4885TDP1 2207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.