SCHEMBL496275

SCHEMBL496275

O=C(O)c1cccc(OC(F)(F)F)c1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 2/20 0.61
AKR1C3 P42330 1/20 0.59
KAT6A Q92794 2/20 0.56
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
NPC1 O15118 1/20 0.53
MITF O75030 1/20 0.53
GAA P10253 1/20 0.53
RAB9A P51151 1/20 0.53
TAS1R3 Q7RTX0 1/20 0.53
TAS1R1 Q7RTX1 1/20 0.53
TAS1R2 Q8TE23 1/20 0.53
NR4A2 P43354 4/20 0.52
EPHX2 P34913 1/20 0.51
AURKA O14965 1/20 0.50
TPX2 Q9ULW0 1/20 0.50
KMO O15229 1/20 0.50
PPARG P37231 1/20 0.50
GPR139 Q6DWJ6 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29459930 1.00 MRGPRX4 (0.61) MRGPRX4AKR1C3KAT6AKMT2AMEN1
SCHEMBL9138055 0.93 AKR1C3 (0.67) MRGPRX4AKR1C3KAT6AKMT2AMEN1
SCHEMBL5515377 0.90 KMO (0.56) MRGPRX4KMT2AMEN1NPC1MITF
SCHEMBL690501 0.87 KAT6A (0.54) MRGPRX4KAT6ATAS1R3TAS1R1TAS1R2
SCHEMBL5712921 0.86 TTR (0.55) MRGPRX4AKR1C3KAT6AKMT2AMEN1
SCHEMBL6107695 0.86 AKR1C3 (0.61) MRGPRX4AKR1C3KMT2AMEN1NPC1
SCHEMBL30668192 0.86 KAT6A (0.57) MRGPRX4AKR1C3KAT6ATAS1R3TAS1R1
SCHEMBL22954042 0.86 KAT6A (0.57) MRGPRX4AKR1C3KAT6ATAS1R3TAS1R1
SCHEMBL10559975 0.86 AKR1C3 (0.56) MRGPRX4AKR1C3KMT2ANPC1RAB9A
SCHEMBL28208860 0.85 KAT6A (0.52) MRGPRX4KAT6ANPC1RAB9ATAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 591 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025098874-A1 ACTIVE COMPOUND COMBINATIONS HAVING FUNGICIDAL/INSECTICIDAL/ACARICIDAL PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 2025-05-15 WO claimed
US-20240341307-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2024-10-17 US claimed
EP-4384012-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2024-06-19 EP claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-115928264-B Preparation method of continuous silicon carbide fiber containing metal in near-stoichiometric ratio 湖南泽睿新材料有限公司 2024-02-20 CN claimed
CN-111295382-B Bridged bicyclic compounds as farnesyl ester X receptor modulators 百时美施贵宝公司 2024-02-02 CN claimed
CN-110678450-B Isoxazole derivatives as nuclear receptor agonists and uses thereof 日东制药株式会社 2023-06-20 CN claimed
WO-2023017155-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-02-16 WO claimed
CN-114967335-A Treatment-free CTP (computer to plate) plate capable of quickly forming image-text area 安徽强邦新材料股份有限公司 2022-08-30 CN claimed
CN-107681052-B Main group metal complexes as p-dopants for organic electronic matrix materials 西门子公司 2020-03-24 CN claimed
CN-106967122-B The main group metal complex compound of p dopant as organic electronic basis material 西门子公司 2019-08-30 CN claimed
US-20180198069-A1 P-Doping Cross-Linking Of Organic Hole Transporters SIEMENS AKTIENGESELLSCHAFT (DE) 2018-07-12 US claimed
EP-3057151-B1 BISMUTH AND TIN COMPLEXES AS P DOTANDS FOR ORGANIC ELECTRONIC MATRIX MATERIALS SIEMENS AG (DE) 2018-01-31 EP claimed
CN-106967122-A The main group metal complex compound of p dopants as organic electronic matrix material 西门子公司 2017-07-21 CN claimed
US-20170098787-A1 MAIN GROUP METAL COMPLEXES AS P-DOPANTS FOR ORGANIC ELECTRONIC MATRIX MATERIALS SIEMENS AKTIENGESELLSCHAFT (DE) 2017-04-06 US claimed
EP-3057151-A1 PRINCIPAL GROUP METAL COMPLEXES AS P DOTANDS FOR ORGANIC ELECTRONIC MATRIX MATERIALS Siemens Aktiengesellschaft (DE) 2016-08-17 EP claimed
EP-2379558-B1 NOVEL HETEROCYCLIC COMPOUNDS FOR USE AS METAP-2 INHIBITORS MERCK PATENT GMBH (DE) 2016-03-23 EP claimed
US-20110281859-A1 NOVEL HETEROCYCLIC COMPOUNDS AS METAP-2 INHIBITORS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-11-17 US claimed
CN-1732161-A 1,3-diamino-2-hydroxypropane pro-drug derivatives ELAN PHARM INC (US) 2006-02-08 CN claimed
US-5219477-A Containing organometallic salts and inorganic metal borates; fromo reactinmetal hydroxide with phenols or aromatic carboxylic acid THE DOW CHEMICAL COMPANY (US) 1993-06-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170098787-A1 MAIN GROUP METAL COMPLEXES AS P-DOPANTS FOR ORGANIC ELECTRONIC MATRIX MATERIALS SCO2, SOD3, NCOA3 MRGPRX4 4549/4885AKR1C3 2057/4885KAT6A 1416/4885
US-20110281859-A1 NOVEL HETEROCYCLIC COMPOUNDS AS METAP-2 INHIBITORS METAP2, METAP1, XPNPEP2 MRGPRX4 114/4885AKR1C3 2374/4885KAT6A 4718/4885
US-20240341307-A1 FUNGICIDAL COMPOSITIONS CBR3, CNPY3, C1R MRGPRX4 2030/4885AKR1C3 8/4885KAT6A 4372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.