Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 18/20 | 1.00 |
| ▸ | SULT1A1 | P50225 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flutemetamol SCHEMBL10032130 | 1.00 | APP (1.00) | APPSULT1A1MAPT | |
| Flutemetamol F 18 SCHEMBL29363499 | 1.00 | APP (1.00) | APPSULT1A1MAPT | |
| Flutemetamol F 18 SCHEMBL10032147 | 1.00 | APP (1.00) | APPSULT1A1MAPT | |
| SCHEMBL5958763 | 0.87 | APP (0.77) | APPSULT1A1MAPT | |
| SCHEMBL14788828 | 0.86 | APP (0.75) | APPSULT1A1MAPT | |
| SCHEMBL15604181 | 0.86 | APP (0.75) | APPMAPT | |
| SCHEMBL13167852 | 0.85 | APP (0.73) | APPSULT1A1MAPT | |
| SCHEMBL2061295 | 0.85 | APP (1.00) | APPSULT1A1MAPT | |
| SCHEMBL12227066 | 0.85 | APP (1.00) | APPSULT1A1MAPT | |
| SCHEMBL13806265 | 0.84 | APP (0.73) | APPSULT1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12311036-B2 | Metal oxides nanoparticles conjugated with naphthalene derivatives as contrast agents for the detection of beta amyloid plaques by magnetic resonance images | CENTRO DE NEUROCIENCIAS DE CUBA (CU) | 2025-05-27 | — | — | US | disclosed |
| CN-113226381-B | Naphthalene derivative conjugated metal oxide nanoparticles as contrast agents for detection of beta-amyloid plaques by magnetic resonance imaging | 古巴神经科学中心 | 2023-09-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12311036-B2 | Metal oxides nanoparticles conjugated with naphthalene derivatives as contrast agents for the detection of beta amyloid plaques by magnetic resonance images | L1CAM, NUCB2, TSPO | APP 6/4885SULT1A1 2631/4885MAPT 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.