Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 12/20 | 0.79 |
| ▸ | GRIN3B | O60391 | 12/20 | 0.79 |
| ▸ | GRIN1 | Q05586 | 12/20 | 0.79 |
| ▸ | GRIN2A | Q12879 | 12/20 | 0.79 |
| ▸ | GRIN2B | Q13224 | 12/20 | 0.79 |
| ▸ | GRIN2C | Q14957 | 12/20 | 0.79 |
| ▸ | GRIN3A | Q8TCU5 | 12/20 | 0.79 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.79 |
| ▸ | ADRA1D | P25100 | 7/20 | 0.79 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.79 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.79 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18115460 | 1.00 | GRIN2D (0.79) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6439995 | 0.89 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL29756093 | 0.81 | GRIN2D (0.59) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6440014 | 0.80 | GRIN2D (0.58) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL16713384 | 0.79 | GRIN2D (0.79) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL465754 | 0.76 | GRIN2D (0.57) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1811254 | 0.76 | GRIN2D (0.57) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL2378294 | 0.75 | HRH4 (0.60) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL30349346 | 0.75 | HRH4 (0.60) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7480559 | 0.75 | GRIN2D (0.76) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112707893-B | 1-cyanopyrrolidine compounds as USP30 inhibitors | 特殊治疗有限公司 | 2023-10-31 | — | — | CN | disclosed |