Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.55 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 4/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 4/20 | 0.36 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.36 |
| ▸ | LAP3 | P28838 | 4/20 | 0.34 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28564227 | 0.89 | SLC7A5 (0.47) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL4658496 | 0.88 | SLC7A5 (0.43) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL28534814 | 0.86 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL15173245 | 0.85 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL15173244 | 0.85 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL10588085 | 0.85 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL28518732 | 0.84 | ANPEP (0.53) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL8585917 | 0.84 | SLC7A5 (0.53) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL3056494 | 0.79 | SLC7A5 (0.57) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL31116850 | 0.76 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8443799-B2 | Dry powder inhalation system for transpulmonary administration | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-05-21 | — | — | US | disclosed |
| US-8333193-B2 | Dry powder inhalation system for transpulmonary administration | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| US-7735485-B2 | Dry powder inhalation system for transpulmonary administration | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-15 | — | — | US | disclosed |
| US-20090126732-A1 | DRY POWDER INHALATION SYSTEM FOR TRANSPULMONARY ADMINISTRATION | OTSUKA PHARMACEUTICAL CO., LTD. | 2009-05-21 | — | — | US | disclosed |
| US-20090095293-A1 | DRY POWDER INHALATION SYSTEM FOR TRANSPULMONARY ADMINISTRATION | OTSUKA PHARMACEUTICAL CO., LTD. | 2009-04-16 | — | — | US | disclosed |
| US-7448379-B2 | Inhalation system for transpulmonary administration according to which a freeze-dried composition provided housed in a vessel can be prepared into a form suitable for transpulmonary administration by being made into fine particles at the time of use, and administered by inhalation as is | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-11-11 | — | — | US | disclosed |
| US-20070065371-A2 | Novel Dry Powder Inhalation System For Transpulmonary Administration | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-22 | — | — | US | disclosed |
| EP-1402913-B1 | DRY POWDER INHALATION SYSTEM FOR TRANSPULMONARY ADMINISTRATION, METHOD OF MANUFACTURING A DRY POWDERED PREPARATION, AND USE OF A FREEZE DRIED COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2006-08-23 | — | — | EP | disclosed |
| EP-1688133-A1 | Freeze-dried composition for transpulmonary administration | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-08-09 | — | — | EP | disclosed |
| EP-1688134-A2 | Dry powder inhaler for transpulmonary administration | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-08-09 | — | — | EP | disclosed |
| US-20060073105-A1 | Novel dry powder inhalation system for transpulmonary administration | YAMASHITA CHIKAMASA | 2006-04-06 | — | — | US | disclosed |
| EP-1579855-A1 | NOVEL DRY POWDER INHALATION SYSTEM FOR TRANSPULMONARY ADMINISTRATION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-09-28 | — | — | EP | disclosed |
| EP-1402913-A1 | DRY POWDER INHALATION SYSTEM FOR TRANSPULMONARY ADMINISTRATION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-20030101995-A1 | Dry powder inhalation system for transpulmonary administration | OTSUKA PHARMACEUTICAL CO., LTD. | 2003-06-05 | — | — | US | disclosed |