SCHEMBL4658496

SCHEMBL4658496

CCC(C)C(N)C(=O)N(C(=O)C(N)CC(C)C)C(C(=O)O)C(C)C

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.43
SLC1A3 P43003 4/20 0.36
SLC1A2 P43004 4/20 0.36
SLC1A1 P43005 3/20 0.33
DPP4 P27487 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
LAP3 P28838 2/20 0.31
ANPEP P15144 1/20 0.30
RNPEP Q9H4A4 1/20 0.30
DNPEP Q9ULA0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3066899 0.88 SLC7A5 (0.55) SLC7A5SLC1A3SLC1A2SLC1A1LAP3
SCHEMBL28564227 0.81 SLC7A5 (0.47) SLC7A5SLC1A3SLC1A2SLC1A1LAP3
SCHEMBL4982176 0.80 SLC7A5 (0.41) SLC7A5DPP4DPP8DPP9
SCHEMBL4966689 0.77 SLC7A5 (0.38) SLC7A5SLC1A3SLC1A2SLC1A1DPP4
SCHEMBL3396707 0.75 SLC7A5 (0.37) SLC7A5SLC1A3SLC1A2SLC1A1DPP4
SCHEMBL28534814 0.75 SLC7A5 (0.44) SLC7A5SLC1A3SLC1A2SLC1A1LAP3
SCHEMBL15173244 0.75 SLC7A5 (0.55) SLC7A5SLC1A3SLC1A2SLC1A1LAP3
SCHEMBL10588085 0.75 SLC7A5 (0.55) SLC7A5SLC1A3SLC1A2SLC1A1LAP3
SCHEMBL15173245 0.75 SLC7A5 (0.55) SLC7A5SLC1A3SLC1A2SLC1A1LAP3
SCHEMBL28518732 0.74 ANPEP (0.53) SLC7A5SLC1A3SLC1A2SLC1A1ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1018345-B1 WATER SOLUBLE DRY COMPOSITIONS OTSUKA PHARMA CO LTD (JP) 2008-12-10 EP disclosed
US-20080050438-A1 Dry compositions OTSUKA PHARMACEUTICAL CO., LTD. 2008-02-28 US disclosed
EP-1254944-B1 DRY COMPOSITIONS CONTAINING HYDROPHOBIC AMINO ACID OTSUKA PHARMA CO LTD (JP) 2007-03-28 EP disclosed
US-20060057106-A1 Freeze-dried interferon-y composition for transpulmonary administration and inhalation system therefor OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-03-16 US disclosed
EP-1569681-A1 FREEZE-DRIED INTERFERON-GAMMAD; COMPOSITION FOR TRANSPULMONARY ADMINISTRATION AND INHALATION SYSTEM THEREFOR OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-09-07 EP disclosed
EP-0869816-B1 DRY COMPOSITIONS COMPRISING HYDROPHOBIC STABILIZERS OTSUKA PHARMA CO LTD (JP) 2004-12-15 EP disclosed
WO-2004054605-A1 FREEZE-DRIED INTERFERON-Ϝ COMPOSITION FOR TRANSPULMONARY ADMINISTRATION AND INHALATION SYSTEM THEREFOR OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2004-07-01 WO disclosed
EP-1424066-A1 Dry compositions comprising hydrophobic stabilisers OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2004-06-02 EP disclosed
US-20030138402-A1 Dry compositions OTSUKA PHARMACEUTICAL CO., LTD. 2003-07-24 US disclosed
US-20030045481-A1 Dry compositions containing hydrophobic amino acid OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2003-03-06 US disclosed
US-6479048-B2 FOAM INHIBITOR COMPRISING HYDROPHOBIC AMINO ACID WHICH IS SUITABLE FOR INHIBITING FOAMING INDUCED WHEN DISSOLVING A DRY COMPOSITION CONTAINING SACCHARIDE; PREFERABLY HAS A HYDROPATHY INDEX OF NOT LESS THAN 2. OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2002-11-12 US disclosed
EP-1254944-A1 DRY COMPOSITIONS CONTAINING HYDROPHOBIC AMINO ACID OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2002-11-06 EP disclosed
US-6337067-B1 FOR INHIBITING FOAMING CAUSED WHEN DISSOLVING A CONVENTIONAL DRY COMPOSITION CONTAINING A SACCHARIDE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2002-01-08 US disclosed
US-20010049361-A1 Water-soluble dry compositions OTSUKA PHARMACEUTICAL CO., LTD. 2001-12-06 US disclosed
EP-1018345-A1 WATER SOLUBLE DRY COMPOSITIONS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2000-07-12 EP disclosed