Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 9/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 2/20 | 0.32 |
| ▸ | MDM4 | O15151 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21680695 | 1.00 | SCN9A (0.35) | SCN9AFPR2SYKSIRT6PIK3CA | |
| SCHEMBL21680693 | 1.00 | SCN9A (0.35) | SCN9AFPR2SYKSIRT6PIK3CA | |
| SCHEMBL17374001 | 0.83 | SYK (0.38) | SCN9AFPR2SYKSIRT6PIK3CA | |
| SCHEMBL30627275 | 0.80 | KAT2B (0.37) | — | |
| SCHEMBL15110157 | 0.80 | KAT2B (0.37) | — | |
| SCHEMBL27039743 | 0.79 | ALDH1A1 (0.41) | — | |
| SCHEMBL27039744 | 0.79 | ALDH1A1 (0.41) | — | |
| SCHEMBL31661104 | 0.79 | ALDH1A1 (0.41) | — | |
| SCHEMBL31291010 | 0.76 | SCN9A (0.39) | SCN9AFPR2SYK | |
| SCHEMBL27039419 | 0.76 | SCN9A (0.39) | SCN9AFPR2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566915-B | Thiadiazole IRAK4 inhibitors | 吉利德科学公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-112533924-B | Pyrrolo [1,2-b ] pyridazine derivatives as IRAK4 inhibitors | 吉利德科学公司 | 2023-11-28 | — | — | CN | disclosed |