Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TK2 | O00142 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25401212 | 1.00 | TDP1 (0.31) | TDP1TSHRLMNAMAPTPMP22 | |
| SCHEMBL25399246 | 0.90 | — | — | |
| SCHEMBL25399881 | 0.90 | TSHR (0.36) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL25400267 | 0.89 | TSHR (0.34) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL25400259 | 0.89 | TSHR (0.34) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL31572672 | 0.88 | TSHR (0.31) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL26601006 | 0.82 | TYMS (0.31) | TDP1TSHRLMNAMAPTPMP22 | |
| SCHEMBL25399189 | 0.81 | TYMS (0.34) | LMNAMAPTSMN1; SMN2 | |
| SCHEMBL2310943 | 0.80 | CYP2D6 (0.33) | LMNASMN1; SMN2 | |
| SCHEMBL30560917 | 0.80 | CYP2D6 (0.33) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178133-A9 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |