Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 11/20 | 0.60 |
| ▸ | TP53 | P04637 | 6/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26600809 | 1.00 | POLB (0.61) | POLBLMNATP53RXFP1MAPT | |
| SCHEMBL26600948 | 0.95 | POLB (0.61) | POLBLMNATP53RXFP1MAPT | |
| SCHEMBL30670711 | 0.89 | LMNA (0.53) | POLBLMNATP53RXFP1MAPT | |
| SCHEMBL26601228 | 0.89 | LMNA (0.53) | POLBLMNATP53RXFP1MAPT | |
| SCHEMBL26601173 | 0.86 | LMNA (0.68) | POLBLMNATP53RXFP1MAPT | |
| SCHEMBL26601264 | 0.84 | MAPT (0.60) | POLBLMNATP53RXFP1MAPT | |
| SCHEMBL26600982 | 0.83 | LMNA (0.67) | POLBLMNATP53RXFP1MAPT | |
| SCHEMBL26600997 | 0.81 | POLB (0.56) | POLBLMNATP53RXFP1MAPT | |
| SCHEMBL26601280 | 0.79 | LMNA (0.69) | POLBLMNATP53RXFP1MAPT | |
| SCHEMBL26601140 | 0.78 | LMNA (0.72) | POLBLMNATP53RXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4511112-A1 | TRANSCRIPTION FACTOR EB ACTIVATORS AND USES THEREOF | Astellas Engineered Small Molecules US, Incorporated (US) | 2025-02-26 | — | — | EP | claimed |
| WO-2023205415-A1 | TRANSCRIPTION FACTOR EB ACTIVATORS AND USES THEREOF | MITOBRIDGE INC. (US) | 2023-10-26 | — | — | WO | claimed |
| EP-4511112-A1 | TRANSCRIPTION FACTOR EB ACTIVATORS AND USES THEREOF | Astellas Engineered Small Molecules US, Incorporated (US) | 2025-02-26 | — | — | EP | disclosed |
| WO-2023205415-A1 | TRANSCRIPTION FACTOR EB ACTIVATORS AND USES THEREOF | MITOBRIDGE INC. (US) | 2023-10-26 | — | — | WO | disclosed |