Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26601211 | 1.00 | LMNA (0.58) | LMNATP53RXFP1MEN1KMT2A | |
| SCHEMBL26601012 | 0.89 | LMNA (0.68) | LMNATP53RXFP1MEN1KMT2A | |
| SCHEMBL30670743 | 0.89 | LMNA (0.54) | LMNATP53RXFP1THRBMAPT | |
| SCHEMBL26601149 | 0.89 | LMNA (0.54) | LMNATP53RXFP1THRBMAPT | |
| SCHEMBL26601332 | 0.87 | LMNA (0.61) | LMNATP53RXFP1MEN1KMT2A | |
| SCHEMBL26600962 | 0.86 | TP53 (0.60) | LMNATP53RXFP1MEN1KMT2A | |
| SCHEMBL26601385 | 0.86 | POLB (0.67) | LMNATP53RXFP1MEN1KMT2A | |
| SCHEMBL30670758 | 0.86 | POLB (0.67) | LMNATP53RXFP1MEN1KMT2A | |
| SCHEMBL30670760 | 0.86 | TP53 (0.62) | LMNATP53RXFP1MEN1KMT2A | |
| SCHEMBL26601240 | 0.86 | TP53 (0.62) | LMNATP53RXFP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4511112-A1 | TRANSCRIPTION FACTOR EB ACTIVATORS AND USES THEREOF | Astellas Engineered Small Molecules US, Incorporated (US) | 2025-02-26 | — | — | EP | disclosed |
| WO-2023205415-A1 | TRANSCRIPTION FACTOR EB ACTIVATORS AND USES THEREOF | MITOBRIDGE INC. (US) | 2023-10-26 | — | — | WO | disclosed |