SCHEMBL30672603

SCHEMBL30672603

N=C(N)NCCC[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ BDKRB2 P30411 6/20 0.66
▸ OPRM1 P35372 6/20 0.57
▸ OPRD1 P41143 4/20 0.57
▸ C5AR1 P21730 1/20 0.55
▸ F2 P00734 1/20 0.54
▸ NMUR2 Q9GZQ4 1/20 0.52
▸ NMUR1 Q9HB89 1/20 0.52
▸ OPRK1 P41145 2/20 0.52
▸ CXCR4 P61073 1/20 0.52
▸ EPHA2 P29317 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31289571 1.00 BDKRB2 (0.66) BDKRB2OPRM1OPRD1C5AR1F2
SCHEMBL31289572 0.99 BDKRB2 (0.66) BDKRB2OPRM1OPRD1C5AR1F2
SCHEMBL25335885 0.99 BDKRB2 (0.68) BDKRB2OPRM1OPRD1C5AR1F2
SCHEMBL30526215 0.99 BDKRB2 (0.68) BDKRB2OPRM1OPRD1C5AR1F2
SCHEMBL30549403 0.96 BDKRB2 (0.63) BDKRB2OPRM1OPRD1C5AR1F2
SCHEMBL30672572 0.96 BDKRB2 (0.72) BDKRB2OPRM1OPRD1NMUR2NMUR1
SCHEMBL31289567 0.95 BDKRB2 (0.59) BDKRB2OPRM1OPRD1F2NMUR2
SCHEMBL29496923 0.94 BDKRB2 (0.62) BDKRB2OPRM1OPRD1C5AR1F2
SCHEMBL31289576 0.94 BDKRB2 (0.58) BDKRB2OPRM1OPRD1NMUR2NMUR1
SCHEMBL30526200 0.93 BDKRB2 (0.61) BDKRB2OPRM1OPRD1C5AR1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12558420-B2 Methods for treating inflammation using antibodies to kallidin and des-Arg10-kallidin SANOFI (FR) 2026-02-24 — — US disclosed
US-20230399388-A1 METHODS FOR TREATING INFLAMMATION USING ANTIBODIES TO KALLIDIN AND DES-ARG10-KALLIDIN SANOFI (FR) 2023-12-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558420-B2 Methods for treating inflammation using antibodies to kallidin and des-Arg10-kallidin BDKRB2, KLKB1, BDKRB1 BDKRB2 1/4885OPRM1 945/4885OPRD1 819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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