Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.52 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.52 |
| ▸ | PRKACA | P17612 | 2/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.52 |
| ▸ | AKT1 | P31749 | 2/20 | 0.52 |
| ▸ | GSK3A | P49840 | 2/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.52 |
| ▸ | NEK4 | P51957 | 2/20 | 0.52 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.52 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.52 |
| ▸ | PRKG2 | Q13237 | 2/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.52 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.52 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.52 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27249149 | 0.93 | AURKB (0.58) | FLT4CNR1CHEK1MAP4K4CHEK2 | |
| SCHEMBL30672911 | 0.86 | KMT2A (0.52) | FLT4CNR1CHEK1MAP4K4CHEK2 | |
| SCHEMBL30672966 | 0.86 | CHEK2 (0.52) | FLT4CNR1CHEK1MAP4K4CHEK2 | |
| SCHEMBL30673004 | 0.86 | MEN1 (0.62) | FLT4CNR1CHEK1MAP4K4CHEK2 | |
| SCHEMBL30672940 | 0.85 | CNR1 (0.55) | FLT4CNR1CHEK1MAP4K4CHEK2 | |
| SCHEMBL30673046 | 0.84 | CNR1 (0.56) | FLT4CNR1CHEK1MAP4K4CHEK2 | |
| SCHEMBL4366760 | 0.83 | FLT4 (0.67) | FLT4CHEK1MAP4K4CHEK2PRKACA | |
| SCHEMBL30673142 | 0.83 | GSK3B (0.67) | FLT4CHEK1MAP4K4CHEK2PRKACA | |
| SCHEMBL4369721 | 0.83 | GSK3A (0.75) | FLT4CHEK1MAP4K4CHEK2PRKACA | |
| SCHEMBL30672914 | 0.83 | CNR1 (0.55) | FLT4CNR1CHEK1MAP4K4CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119325464-A | Square amide derivatives as CB1 allosteric modulators | 研究三角协会 | 2025-01-17 | — | — | CN | claimed |
| EP-4532463-A1 | SQUARAMIDE DERIVATIVES AS CB1 ALLOSTERIC MODULATORS | Research Triangle Institute (US) | 2025-04-09 | — | — | EP | disclosed |
| CN-119325464-A | Square amide derivatives as CB1 allosteric modulators | 研究三角协会 | 2025-01-17 | — | — | CN | disclosed |
| WO-2023235548-A1 | SQUARAMIDE DERIVATIVES AS CB1 ALLOSTERIC MODULATORS | RESEARCH TRIANGLE INSTITUTE (US) | 2023-12-07 | — | — | WO | disclosed |