Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.67 |
| ▸ | CHEK2 | O96017 | 6/20 | 0.67 |
| ▸ | PRKACA | P17612 | 6/20 | 0.67 |
| ▸ | RPS6KB1 | P23443 | 6/20 | 0.67 |
| ▸ | GSK3A | P49840 | 6/20 | 0.67 |
| ▸ | RPS6KA3 | P51812 | 6/20 | 0.67 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.67 |
| ▸ | PRKG1 | Q13976 | 6/20 | 0.67 |
| ▸ | PKN2 | Q16513 | 6/20 | 0.67 |
| ▸ | CDC42BPA | Q5VT25 | 6/20 | 0.67 |
| ▸ | HIPK4 | Q8NE63 | 6/20 | 0.67 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.67 |
| ▸ | CSNK1G3 | Q9Y6M4 | 6/20 | 0.67 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.67 |
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.67 |
| ▸ | SGK2 | Q9HBY8 | 5/20 | 0.67 |
| ▸ | AKT1 | P31749 | 5/20 | 0.67 |
| ▸ | NEK4 | P51957 | 4/20 | 0.67 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.67 |
| ▸ | CSNK1G2 | P78368 | 4/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4369721 | 0.94 | GSK3A (0.75) | GSK3BCHEK2PRKACARPS6KB1GSK3A | |
| SCHEMBL4376009 | 0.90 | FLT4 (0.71) | GSK3BCHEK2PRKACARPS6KB1GSK3A | |
| SCHEMBL27249149 | 0.90 | AURKB (0.58) | GSK3BCHEK2PRKACARPS6KB1GSK3A | |
| SCHEMBL4026017 | 0.87 | FLT4 (0.80) | GSK3BCHEK2PRKACARPS6KB1GSK3A | |
| SCHEMBL30673004 | 0.86 | MEN1 (0.62) | GSK3BCHEK2PRKACARPS6KB1GSK3A | |
| SCHEMBL30672966 | 0.83 | CHEK2 (0.52) | GSK3BCHEK2PRKACARPS6KB1GSK3A | |
| SCHEMBL30673085 | 0.83 | FLT4 (0.52) | GSK3BCHEK2PRKACARPS6KB1GSK3A | |
| SCHEMBL30672911 | 0.83 | KMT2A (0.52) | GSK3BCHEK2PRKACARPS6KB1GSK3A | |
| SCHEMBL4364173 | 0.83 | FLT4 (0.79) | GSK3BCHEK2PRKACARPS6KB1GSK3A | |
| SCHEMBL30672940 | 0.83 | CNR1 (0.55) | GSK3BCHEK2PRKACARPS6KB1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119325464-A | Square amide derivatives as CB1 allosteric modulators | 研究三角协会 | 2025-01-17 | — | — | CN | claimed |
| EP-4532463-A1 | SQUARAMIDE DERIVATIVES AS CB1 ALLOSTERIC MODULATORS | Research Triangle Institute (US) | 2025-04-09 | — | — | EP | disclosed |
| CN-119325464-A | Square amide derivatives as CB1 allosteric modulators | 研究三角协会 | 2025-01-17 | — | — | CN | disclosed |
| WO-2023235548-A1 | SQUARAMIDE DERIVATIVES AS CB1 ALLOSTERIC MODULATORS | RESEARCH TRIANGLE INSTITUTE (US) | 2023-12-07 | — | — | WO | disclosed |