SCHEMBL30673522

SCHEMBL30673522

CSc1nc(-c2cccc(NC(=O)CN3CCSCC3)c2)c2c(N)c(C(=O)NC(C)(C)C)sc2n1

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LHCGR P22888 16/20 0.64
FSHR P23945 5/20 0.63
TSHR P16473 2/20 0.63
BRAF P15056 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5026093 1.00 LHCGR (0.64) LHCGRFSHRTSHRBRAF
SCHEMBL5028842 0.94 LHCGR (0.67) LHCGRFSHRTSHR
SCHEMBL30673524 0.94 LHCGR (0.67) LHCGRFSHRTSHR
SCHEMBL5028832 0.94 LHCGR (0.67) LHCGRFSHRTSHR
SCHEMBL30673520 0.94 LHCGR (0.67) LHCGRFSHRTSHR
SCHEMBL30673521 0.93 LHCGR (0.66) LHCGRFSHRTSHR
SCHEMBL5025963 0.93 LHCGR (0.66) LHCGRFSHRTSHR
SCHEMBL5026884 0.92 LHCGR (0.64) LHCGRFSHRTSHR
SCHEMBL5025965 0.92 LHCGR (0.64) LHCGRFSHRTSHR
SCHEMBL30673525 0.92 LHCGR (0.64) LHCGRFSHRTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119894515-A Methods of treating obesity with luteinizing hormone receptor agonists 西奈山伊坎医学院 2025-04-25 CN claimed
EP-4536352-A2 METHOD OF TREATING OBESITY WITH A LUTEINIZING HORMONE RECEPTOR AGONIST Icahn School of Medicine at Mount Sinai (US) 2025-04-16 EP claimed
WO-2023239854-A2 METHOD OF TREATING OBESITY WITH A LUTEINIZING HORMONE RECEPTOR AGONIST ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2023-12-14 WO claimed
CN-119894515-A Methods of treating obesity with luteinizing hormone receptor agonists 西奈山伊坎医学院 2025-04-25 CN disclosed
EP-4536352-A2 METHOD OF TREATING OBESITY WITH A LUTEINIZING HORMONE RECEPTOR AGONIST Icahn School of Medicine at Mount Sinai (US) 2025-04-16 EP disclosed
WO-2023239854-A2 METHOD OF TREATING OBESITY WITH A LUTEINIZING HORMONE RECEPTOR AGONIST ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2023-12-14 WO disclosed