SCHEMBL30674367

SCHEMBL30674367

Cc1ccc(S(=O)(=O)n2cc(I)c3c(Br)ccnc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.46
CA2 P00918 3/20 0.44
CA1 P00915 2/20 0.44
POLB P06746 1/20 0.42
ALDH3A1 P30838 1/20 0.42
HTT P42858 1/20 0.42
NOD1 Q9Y239 1/20 0.42
RAPGEF4 Q8WZA2 1/20 0.38
BRD4 O60885 1/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
GAA P10253 1/20 0.35
KDM4E B2RXH2 1/20 0.35
UBE2N P61088 1/20 0.35
ABL1 P00519 1/20 0.35
BCR P11274 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.34
PKM P14618 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26930315 1.00 L3MBTL1 (0.46) L3MBTL1CA2CA1POLBALDH3A1
SCHEMBL25238794 0.88 CA1 (0.50) L3MBTL1CA2CA1POLBALDH3A1
SCHEMBL26176315 0.87 L3MBTL1 (0.48) L3MBTL1CA2CA1POLBALDH3A1
SCHEMBL20437149 0.87 L3MBTL1 (0.48) L3MBTL1CA2CA1POLBALDH3A1
SCHEMBL30668758 0.85 L3MBTL1 (0.46) L3MBTL1CA2CA1POLBALDH3A1
SCHEMBL2881500 0.85 L3MBTL1 (0.46) L3MBTL1CA2CA1POLBALDH3A1
SCHEMBL20396845 0.84 CA1 (0.43) L3MBTL1CA2CA1POLBALDH3A1
SCHEMBL31152383 0.82 L3MBTL1 (0.44) L3MBTL1CA2CA1POLBALDH3A1
SCHEMBL1952982 0.82 KDM4E (0.47) L3MBTL1CA2CA1POLBALDH3A1
SCHEMBL29605064 0.82 CA1 (0.49) L3MBTL1CA2CA1POLBALDH3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4536657-A1 LATS INHIBITORS AND USES THEREOF The USA, as represented by The Secretary, Department of Health and Human Services (US) 2025-04-16 EP disclosed
WO-2023239727-A1 LATS INHIBITORS AND USES THEREOF THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) 2023-12-14 WO disclosed