SCHEMBL30674497

SCHEMBL30674497

CC(=O)Nc1cc(Cl)c(C)c2c1C(=O)/C(=N\O)CC2

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
ROCK2 O75116 1/20 0.34
ATAD2 Q6PL18 1/20 0.33
CECR2 Q9BXF3 1/20 0.33
ALDH1A1 P00352 3/20 0.32
LMNA P02545 2/20 0.32
POLB P06746 2/20 0.32
KDM4E B2RXH2 2/20 0.31
HSD17B10 Q99714 1/20 0.31
MAPT P10636 1/20 0.31
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29153537 1.00 MEN1 (0.34) MEN1KMT2ACA1CA2CA9
SCHEMBL30977209 1.00 MEN1 (0.34) MEN1KMT2ACA1CA2CA9
SCHEMBL29153539 1.00 MEN1 (0.34) MEN1KMT2ACA1CA2CA9
Potassium Ion SCHEMBL29084677 0.93 MEN1 (0.36) MEN1KMT2ACA1CA2CA9
SCHEMBL26276091 0.85 CA1 (0.34) CA1CA2CA9MAOA
SCHEMBL7658801 0.82 KMT2A (0.39) MEN1KMT2ACA1CA2CA9
SCHEMBL27218964 0.81 MEN1 (0.34) MEN1KMT2ACA1CA2CA9
SCHEMBL24728326 0.79 CA1 (0.35) MEN1KMT2ACA1CA2CA9
SCHEMBL26623056 0.78 CA1 (0.33) MEN1KMT2ACA1CA2CA9
SCHEMBL26623059 0.78 CA1 (0.33) MEN1KMT2ACA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250281631-A1 ANTIBODY-DRUG CONJUGATES AND PREPARATION METHODS AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2025-09-11 US disclosed
EP-4601701-A1 ANTIBODY-DRUG CONJUGATE BINDING TO HUMAN PTK7 AND METHOD FOR PREPARATION AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2025-08-20 EP disclosed
EP-4594327-A1 LIGAND-DRUG CONJUGATE OF EXATECAN ANALOGUE, AND MEDICAL USE THEREOF BeiGene Switzerland GmbH (CH) 2025-08-06 EP disclosed
CN-120058723-A Camptothecins compound and its preparation method and application 四川科伦博泰生物医药股份有限公司 2025-05-30 CN disclosed
CN-119997983-A Antibody drug conjugate, preparation method and application thereof 四川科伦博泰生物医药股份有限公司 2025-05-13 CN disclosed
CN-119948031-A Ligand-drug conjugates of isatecan analogs and medical uses thereof 广州百济神州生物制药有限公司 2025-05-06 CN disclosed
CN-119899238-A Condensed-cyclic compound, preparation method and application thereof 四川科伦博泰生物医药股份有限公司 2025-04-29 CN disclosed
CN-117567478-B Camptothecins compound and its preparation method and application 四川科伦博泰生物医药股份有限公司 2025-03-21 CN disclosed
EP-4514396-A1 ANTIBODY-DRUG CONJUGATES AND PREPARATION METHODS AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2025-03-05 EP disclosed
CN-119212732-A Antibody drug conjugate, preparation method and application thereof 四川科伦博泰生物医药股份有限公司 2024-12-27 CN disclosed
WO-2024078586-A9 ANTIBODY-DRUG CONJUGATE BINDING TO HUMAN PTK7 AND METHOD FOR PREPARATION AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2024-10-17 WO disclosed
WO-2023208216-A9 ANTIBODY-DRUG CONJUGATES AND PREPARATION METHODS AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2024-08-29 WO disclosed
WO-2024078586-A1 ANTIBODY-DRUG CONJUGATE BINDING TO HUMAN PTK7 AND METHOD FOR PREPARATION AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2024-04-18 WO disclosed
EP-4349372-A1 ANTIBODY DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2024-04-10 EP disclosed
WO-2024067811-A1 LIGAND-DRUG CONJUGATE OF EXATECAN ANALOGUE, AND MEDICAL USE THEREOF BEIGENE, LTD. (KY) 2024-04-04 WO disclosed
CN-117567478-A Camptothecins compound and its preparation method and application 四川科伦博泰生物医药股份有限公司 2024-02-20 CN disclosed
CN-117500527-A Antibody drug conjugate, preparation method and application thereof 四川科伦博泰生物医药股份有限公司 2024-02-02 CN disclosed
WO-2023208216-A1 ANTIBODY-DRUG CONJUGATES AND PREPARATION METHODS AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2023-11-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250281631-A1 ANTIBODY-DRUG CONJUGATES AND PREPARATION METHODS AND USE THEREOF TOP1, TOP2A, TOP2B MEN1 2546/4885KMT2A 980/4885CA1 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.