Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 0.69 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29848915 | 0.82 | BRD4 (1.00) | BRD4METBRD9BRD7 | |
| SCHEMBL16650475 | 0.82 | BRD4 (1.00) | BRD4METBRD9BRD7 | |
| SCHEMBL30675016 | 0.81 | BRD4 (0.56) | BRD4CREBBPSMN1; SMN2NPC1LMNA | |
| SCHEMBL13395622 | 0.73 | MET (0.61) | BRD4CREBBPSMN1; SMN2NPC1LMNA | |
| SCHEMBL30674979 | 0.73 | BRD4 (0.51) | BRD4CREBBPSMN1; SMN2NPC1LMNA | |
| SCHEMBL19592547 | 0.69 | KDM4E (0.56) | BRD4SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL25562613 | 0.68 | CBFB (0.53) | BRD4SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL16651456 | 0.68 | BRD4 (1.00) | BRD4BRD9BRD7 | |
| SCHEMBL29849051 | 0.68 | BRD4 (1.00) | BRD4BRD9BRD7 | |
| SCHEMBL12677163 | 0.68 | COMT (0.51) | BRD4SMN1; SMN2NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111819176-B | 4-azaindole compounds | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | claimed |