SCHEMBL30675007

SCHEMBL30675007

C1CNCC(NC2COC2)C1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.42
MAOB P27338 2/20 0.42
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SLC6A1 P30531 2/20 0.32
KCNH2 Q12809 1/20 0.32
SLC6A11 P48066 1/20 0.32
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SLC6A13 Q9NSD5 1/20 0.32
MAPK1 P28482 1/20 0.32
OPRK1 P41145 1/20 0.32
APLNR P35414 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
NOS2 P35228 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21425603 0.87 KCNH2 (0.43) KDM1AMAOBKCNH2MAOA
SCHEMBL31014268 0.86 KDM1A (0.40) KDM1AMAOBALDH1A1HSD17B10MAPK1
SCHEMBL5968409 0.82 ALDH1A1 (0.52) KDM1AMAOBALDH1A1HSD17B10SLC6A1
SCHEMBL28165037 0.82 KDM1A (0.47) KDM1AMAOBALDH1A1HSD17B10SLC6A1
SCHEMBL24032965 0.82 KDM1A (0.47) KDM1AMAOBALDH1A1HSD17B10SLC6A1
SCHEMBL12520009 0.74 ALDH1A1 (0.61) ALDH1A1HSD17B10SMN1; SMN2KDM4EMAPT
SCHEMBL31083073 0.73 KCNH2 (0.39) KDM1AMAOBKCNH2MAOA
SCHEMBL31082989 0.73 KCNH2 (0.39) KDM1AMAOBKCNH2MAOA
SCHEMBL25106026 0.73 KCNH2 (0.39) KDM1AMAOBKCNH2MAOA
SCHEMBL2157702 0.73 EPHX1 (0.39) KDM1AMAOBALDH1A1HSD17B10KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111819176-B 4-azaindole compounds 百时美施贵宝公司 2023-12-15 CN claimed