Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.52 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.42 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.42 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 4/20 | 0.36 |
| ▸ | PLAU | P00749 | 4/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29122154 | 1.00 | ELANE (0.52) | ELANETEAD1TEAD4TEAD2KDM5A | |
| SCHEMBL29122837 | 0.85 | ELANE (0.58) | ELANEL3MBTL1F2PLAUCTRB1 | |
| SCHEMBL29121783 | 0.83 | ELANE (0.56) | ELANEL3MBTL1F2PLAUCTRB1 | |
| SCHEMBL29121981 | 0.83 | ELANE (0.56) | ELANEL3MBTL1F2PLAUCTRB1 | |
| SCHEMBL28191160 | 0.82 | ELANE (0.55) | ELANE | |
| SCHEMBL29121714 | 0.82 | L3MBTL1 (0.41) | ELANETEAD1TEAD4TEAD2L3MBTL1 | |
| SCHEMBL29121557 | 0.81 | ELANE (0.53) | ELANEKDM4CL3MBTL1F2PLAU | |
| SCHEMBL27514507 | 0.81 | ELANE (0.53) | ELANEL3MBTL1F2PLAUCTRB1 | |
| SCHEMBL30676733 | 0.81 | ELANE (0.53) | ELANEKDM4CL3MBTL1F2PLAU | |
| SCHEMBL29122779 | 0.79 | TEAD1 (0.47) | TEAD1TEAD4TEAD2KDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120419-A | KLK5 bicyclic heteroaromatic inhibitors | 拜奥克里斯特制药公司 | 2023-11-24 | — | — | CN | disclosed |