Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRACR2A | Q9BSW2 | 15/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30677045 | 0.89 | CRACR2A (0.48) | CRACR2AORAI1 | |
| SCHEMBL30677047 | 0.86 | LMNA (0.36) | ORAI1 | |
| SCHEMBL30677114 | 0.85 | PRKCQ (0.41) | CRACR2A | |
| SCHEMBL30677026 | 0.81 | CRACR2A (0.40) | CRACR2AORAI1 | |
| SCHEMBL30677066 | 0.79 | CRACR2A (0.45) | CRACR2APDE10A | |
| SCHEMBL18865624 | 0.76 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL22122029 | 0.76 | STIM1 (0.46) | ORAI1 | |
| SCHEMBL30677244 | 0.75 | CRACR2A (0.43) | CRACR2AORAI1 | |
| SCHEMBL30677050 | 0.75 | CRACR2A (0.45) | CRACR2AORAI1 | |
| SCHEMBL30677014 | 0.74 | TRPV1 (0.38) | ORAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543890-A1 | USP1 INHIBITORS AND USES THEREOF | Forma Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| CN-119731178-A | USP1 inhibitors and uses thereof | 福马治疗有限公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2023250084-A1 | USP1 INHIBITORS AND USES THEREOF | FORMA THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |