Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRACR2A | Q9BSW2 | 16/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | USP1 | O94782 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667988 | 0.84 | CRACR2A (0.56) | CRACR2AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL30677012 | 0.82 | CRACR2A (0.55) | CRACR2AORAI1 | |
| SCHEMBL30677053 | 0.81 | CRACR2A (0.56) | CRACR2AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL30677160 | 0.80 | LOXL2 (0.41) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL31293507 | 0.78 | CRACR2A (0.54) | CRACR2AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL30677031 | 0.78 | CRACR2A (0.53) | CRACR2AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL20006257 | 0.78 | CRACR2A (0.64) | CRACR2AORAI1 | |
| SCHEMBL30677066 | 0.77 | CRACR2A (0.45) | CRACR2AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL1668344 | 0.77 | CRACR2A (0.68) | CRACR2AORAI1 | |
| SCHEMBL1668922 | 0.76 | CRACR2A (0.54) | CRACR2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543890-A1 | USP1 INHIBITORS AND USES THEREOF | Forma Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| CN-119731178-A | USP1 inhibitors and uses thereof | 福马治疗有限公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2023250084-A1 | USP1 INHIBITORS AND USES THEREOF | FORMA THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |