SCHEMBL30677261

SCHEMBL30677261

NNc1cc(Cl)nn2c(I)cnc12

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 6/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL455120 0.76 TTK (0.36) ERN1
SCHEMBL456366 0.75 ERN1 (0.34) ERN1
SCHEMBL104728 0.75 TNF (0.32)
SCHEMBL10279496 0.75
SCHEMBL458151 0.74 ERN1 (0.33) ERN1
SCHEMBL462239 0.73 ERN1 (0.33) ERN1
SCHEMBL10279254 0.72 ERN1 (0.32) ERN1
SCHEMBL470001 0.71 KCNN1 (0.44)
SCHEMBL3037193 0.71 LMNA (0.37)
SCHEMBL458587 0.70 KDM4C (0.36) ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024014885-A1 NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF 일동제약(주) 2024-01-18 WO disclosed