Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.44 |
| ▸ | CHKA | P35790 | 11/20 | 0.43 |
| ▸ | CHKB | Q9Y259 | 3/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1913691 | 1.00 | HCAR1 (0.48) | HCAR1CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL337032 | 0.94 | PIK3CD (0.46) | HCAR1CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL17144080 | 0.94 | PIK3CD (0.46) | HCAR1CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL11981806 | 0.94 | PIK3CD (0.46) | HCAR1CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL17144495 | 0.88 | HCAR1 (0.45) | HCAR1CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL17143824 | 0.88 | HCAR1 (0.45) | HCAR1CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL17143823 | 0.88 | HCAR1 (0.45) | HCAR1CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL16549251 | 0.86 | CCNA2 (0.53) | CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL10137696 | 0.86 | CCNA2 (0.50) | HCAR1CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL4446284 | 0.84 | PIK3CA (0.49) | HCAR1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024014885-A1 | NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF | 일동제약(주) | 2024-01-18 | — | — | WO | disclosed |