Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18769601 | 0.92 | HDAC4 (0.47) | HDAC4 | |
| Hydrochloric Acid SCHEMBL18742657 | 0.90 | HDAC4 (0.46) | HDAC4 | |
| SCHEMBL11971801 | 0.82 | HDAC4 (0.43) | HDAC4 | |
| Hydrochloric Acid SCHEMBL1936835 | 0.80 | HDAC4 (0.42) | HDAC4 | |
| Hydrochloric Acid SCHEMBL29668826 | 0.80 | HDAC4 (0.42) | HDAC4 | |
| SCHEMBL29168195 | 0.79 | HDAC4 (0.35) | HDAC4HDAC6PDE7A | |
| SCHEMBL2335686 | 0.79 | BACE1 (0.43) | HDAC4HDAC6 | |
| SCHEMBL30251559 | 0.79 | HDAC4 (0.33) | HDAC4 | |
| SCHEMBL6904575 | 0.77 | HTR5A (0.34) | HDAC4 | |
| SCHEMBL17982798 | 0.75 | HDAC4 (0.39) | HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117529476-A | Preparation of substituted 1, 2-diamino heterocyclic derivatives and their use as medicaments | 亚飞络思制药公司 | 2024-02-06 | — | — | CN | disclosed |
| WO-2021071843-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | Pipeline Therapeutics, Inc. (US) | 2021-04-15 | — | — | WO | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |