Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | PIKFYVE | Q9Y2I7 | 11/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | FES | P07332 | 1/20 | 0.44 |
| ▸ | FER | P16591 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | FRK | P42685 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31576475 | 0.89 | KDM4E (0.56) | KDM4ELMNAMAPTHPGDPIKFYVE | |
| SCHEMBL30676711 | 0.89 | KDM4E (0.56) | KDM4ELMNAMAPTHPGDPIKFYVE | |
| SCHEMBL31576443 | 0.86 | MAPT (0.61) | KDM4ELMNAMAPTHPGDPIKFYVE | |
| SCHEMBL30677353 | 0.86 | MAPT (0.61) | KDM4ELMNAMAPTHPGDPIKFYVE | |
| SCHEMBL30677453 | 0.84 | MAPT (0.58) | KDM4ELMNAMAPTHPGDPIKFYVE | |
| SCHEMBL31576457 | 0.84 | MAPT (0.58) | KDM4ELMNAMAPTHPGDPIKFYVE | |
| SCHEMBL31576401 | 0.80 | KDM4E (0.60) | KDM4ELMNAMAPTHPGDPIKFYVE | |
| SCHEMBL30677443 | 0.80 | KDM4E (0.60) | KDM4ELMNAMAPTHPGDPIKFYVE | |
| SCHEMBL31576480 | 0.79 | MAPT (0.47) | KDM4ELMNAMAPTHPGDPIKFYVE | |
| SCHEMBL30677388 | 0.79 | MAPT (0.47) | KDM4ELMNAMAPTHPGDPIKFYVE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024014885-A1 | NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF | 일동제약(주) | 2024-01-18 | — | — | WO | disclosed |