SCHEMBL30678112

SCHEMBL30678112

CC(C)(C)OC(=O)CC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NCCOCCOCCOCCOCCOCCC(=O)O

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 1/20 0.46
▸ TLR2 O60603 4/20 0.45
▸ PTPN1 P18031 6/20 0.44
▸ MDM2 Q00987 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21836163 1.00 KMT2A (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL26689778 1.00 KMT2A (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL26689395 1.00 KMT2A (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL30678132 1.00 KMT2A (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL26689779 1.00 KMT2A (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL16757551 1.00 KMT2A (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL26689398 1.00 KMT2A (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL29975272 1.00 KMT2A (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL16757654 0.93 TLR2 (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL31557564 0.93 TLR2 (0.46) KMT2ATLR2PTPN1MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111431-A1 ANTI-CD7 ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF LES LABORATOIRES SERVIER (FR) 2025-05-30 — — WO disclosed
EP-4525928-A1 ANTIBODY DRUG CONJUGATES Novartis AG (CH) 2025-03-26 — — EP disclosed
EP-4525927-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF Novartis AG (CH) 2025-03-26 — — EP disclosed
WO-2023223097-A1 ANTIBODY DRUG CONJUGATES NOVARTIS AG (CH) 2023-11-23 — — WO disclosed
WO-2023225359-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2023-11-23 — — WO disclosed
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