SCHEMBL26689779

SCHEMBL26689779

CC(C)(C)OC(=O)CCC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NCCOCCOCCOCCOCCOCCOCCC(=O)O

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 1/20 0.46
▸ TLR2 O60603 4/20 0.45
▸ PTPN1 P18031 6/20 0.44
▸ MDM2 Q00987 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21836163 1.00 KMT2A (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL26689778 1.00 KMT2A (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL26689395 1.00 KMT2A (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL30678132 1.00 KMT2A (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL16757551 1.00 KMT2A (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL30678112 1.00 KMT2A (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL26689398 1.00 KMT2A (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL29975272 1.00 KMT2A (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL16757654 0.93 TLR2 (0.46) KMT2ATLR2PTPN1MDM2
SCHEMBL31557564 0.93 TLR2 (0.46) KMT2ATLR2PTPN1MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260061065-A1 ANTIBODY DRUG CONJUGATES NOVARTIS AG (CH) 2026-03-05 — — US disclosed
US-20250387504-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2025-12-25 — — US disclosed
WO-2023225359-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2023-11-23 — — WO disclosed
WO-2023223097-A1 ANTIBODY DRUG CONJUGATES NOVARTIS AG (CH) 2023-11-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250387504-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF BID, BCL2, MCL1 KMT2A 719/4885TLR2 4179/4885PTPN1 1566/4885
US-20260061065-A1 ANTIBODY DRUG CONJUGATES FCGR2A, FCGR3B, BCL3 KMT2A 2434/4885TLR2 1153/4885PTPN1 1879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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