Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 12/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30678292 | 0.87 | GRM5 (0.43) | GRM5CA12CA1CA2CA9 | |
| SCHEMBL30678274 | 0.87 | CA12 (0.38) | GRM5FFAR1CA12CA1CA2 | |
| SCHEMBL24222499 | 0.83 | DRD2 (0.50) | DRD2DRD3 | |
| SCHEMBL29729900 | 0.83 | DRD2 (0.50) | DRD2DRD3 | |
| SCHEMBL28682163 | 0.83 | HTR2C (0.42) | CA12CA1CA2CA9DRD2 | |
| SCHEMBL24454842 | 0.83 | HTR2C (0.42) | CA12CA1CA2CA9DRD2 | |
| SCHEMBL29649085 | 0.83 | DRD2 (0.50) | DRD2DRD3 | |
| SCHEMBL22456248 | 0.83 | DRD2 (0.50) | DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL31200371 | 0.82 | DRD2 (0.49) | DRD2DRD3 | |
| SCHEMBL30678299 | 0.81 | HAO1 (0.35) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117255792-A | Heteroaryl derivatives, process for preparing the same and pharmaceutical compositions comprising the same as active ingredient | 沃若诺伊公司 | 2023-12-19 | — | — | CN | disclosed |