Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LIPA | P38571 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | YEATS4 | O95619 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30679068 | 0.99 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTRAB9ANPC1HTT | |
| SCHEMBL29118944 | 0.72 | ALDH1A1 (0.40) | SMN1; SMN2MAPTRAB9ANPC1HTT | |
| SCHEMBL29123363 | 0.71 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTRAB9ANPC1HTT | |
| SCHEMBL30676084 | 0.71 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTRAB9ANPC1HTT | |
| SCHEMBL29026363 | 0.70 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTRAB9ANPC1HTT | |
| SCHEMBL30676088 | 0.70 | MAPT (0.43) | SMN1; SMN2MAPTRAB9ANPC1HTT | |
| SCHEMBL31629008 | 0.68 | ALDH1A1 (0.51) | SMN1; SMN2MAPTRAB9ANPC1HTT | |
| SCHEMBL29026371 | 0.68 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTRAB9ANPC1HTT | |
| SCHEMBL12221433 | 0.67 | MEN1 (0.38) | SMN1; SMN2HTTALDH1A1TSHRMEN1 | |
| SCHEMBL28443870 | 0.67 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTRAB9ANPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757884-B | Substituted macrocyclic indole derivatives | 拜耳股份公司 | 2023-12-19 | — | — | CN | disclosed |