Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK2 | Q92630 | 17/20 | 1.00 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.64 |
| ▸ | CCND1 | P24385 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26447920 | 1.00 | DYRK2 (1.00) | DYRK2CDK6CCND1 | |
| SCHEMBL32677351 | 0.90 | DYRK2 (1.00) | DYRK2CDK6CCND1 | |
| SCHEMBL26447945 | 0.90 | DYRK2 (1.00) | DYRK2CDK6CCND1 | |
| SCHEMBL26447927 | 0.90 | DYRK2 (1.00) | DYRK2CDK6 | |
| Hydrochloric Acid SCHEMBL26680013 | 0.90 | DYRK2 (0.99) | DYRK2CDK6 | |
| SCHEMBL30569709 | 0.89 | DYRK2 (1.00) | DYRK2 | |
| SCHEMBL26447926 | 0.89 | DYRK2 (1.00) | DYRK2 | |
| SCHEMBL30679279 | 0.88 | DYRK2 (1.00) | DYRK2CDK6CCND1 | |
| SCHEMBL26447922 | 0.88 | DYRK2 (1.00) | DYRK2CDK6CCND1 | |
| SCHEMBL26447898 | 0.88 | DYRK2 (0.84) | DYRK2CDK6CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282864-A1 | CDK6/DYRK2 DUAL-TARGET INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Tasly Diyi Pharmaceutical Co., Ltd. (CN) | 2023-11-29 | — | — | EP | disclosed |